Derived from early blastocyst embryos, human embryonic stem cells (hESC) are self-renewable cells with pluripotency. Under special culture conditions, neural cells can be generated from hESC including glial cells, functional neurons, and oligodendrocytes. To avoid other lineage cells as contaminants, the neural progenitor (NP) cell population is necessary to the neural lineage and has been served as an unlimited lineage-restricted cell source for therapeutic and research. Learn more: neural stem cell differentiation
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Novel Antibacterial Compounds Targeting FtsZ Protein
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Oxazolidinones are characterized by a five-membered heterocyclic ring containing oxygen and nitrogen atoms, forming the core structure of the compound. This unique molecular arrangement imparts specific pharmacological properties crucial for their antibacterial activity. Key members of this class include linezolid and tedizolid, which have gained prominence in clinical practice. Fernandes [1] explored the development and evaluation of innovative antibacterial compounds based on oxazolidinones specifically designed to target the FtsZ protein, a pivotal player in bacterial cell division processes. This strategic focus on FtsZ arises from its essential role in bacterial viability, making it an attractive target for antibacterial agents aimed at disrupting crucial cellular functions. Learn more: Synthetic Chemistry Services.
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