Lesion-induced cellular models

Lesion-induced cellular models provide controlled environments to study neurodegeneration, repair mechanisms, and therapeutic responses. These models simulate critical pathological conditions, including neuroinflammation, excitotoxicity, and oxidative stress, by applying specific proteins or chemical compounds to replicate disease features.

Applications include:

Alzheimer’s Disease (AD): Mimicking Aβ and tau pathology

Parkinson’s Disease (PD): Modeling dopaminergic neuron degeneration

Amyotrophic Lateral Sclerosis (ALS): Inducing motor neuron toxicity

Epilepsy: Studying neuronal hyperexcitability